Reactome | gng7 [plasma membrane]

gng7 [plasma membrane]

Stable Identifier

R-XTR-164325

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

plasma membrane

Synonyms

GNG7, Q28H40

Locations in the PathwayBrowser

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Hemostasis (Xenopus tropicalis)

- Platelet activation, signaling and aggregation (Xenopus tropicalis)
  - Signal amplification (Xenopus tropicalis)
    - ADP signalling through P2Y purinoceptor 12 (Xenopus tropicalis)
      - Gi activation by P2Y purinoceptor 12 (Xenopus tropicalis)
        
        ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein Gi (active) [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
        
        ADP:P2RY12:G-protein Gi (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
    - Thromboxane signalling through TP receptor (Xenopus tropicalis)
      - G13 activation by TP receptor (Xenopus tropicalis)
        
        TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein G13 (active) [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
        
        TP receptor:Thromboxane A2:G-protein G13 (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
      - Gq activation by TP receptor (Xenopus tropicalis)
        
        TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein Gq (active) [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
        
        TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
  - Thrombin signalling through proteinase activated receptors (PARs) (Xenopus tropicalis)
    - Thrombin-activated PARs activate Gq (Xenopus tropicalis)
      - Thrombin-activated PAR:Gq (active) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein Gq (active) [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
      - Thrombin-activated PARs:Gq (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)

Neuronal System (Xenopus tropicalis)

- Potassium Channels (Xenopus tropicalis)
  - Inwardly rectifying K+ channels (Xenopus tropicalis)
    - G protein gated Potassium channels (Xenopus tropicalis)
      - Activation of G protein gated Potassium channels (Xenopus tropicalis)
        
        Activation of GIRK/Kir3 Channels (Xenopus tropicalis)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Xenopus tropicalis)
        
        GABA B receptor G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Xenopus tropicalis)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Xenopus tropicalis)
        
        GABA B receptor G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
        
        GABA B receptor G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
- 传播在穿越s Chemical Synapses (Xenopus tropicalis)
  - Neurotransmitter receptors and postsynaptic signal transmission (Xenopus tropicalis)
    - GABA receptor activation (Xenopus tropicalis)
      - GABA B receptor activation (Xenopus tropicalis)
        
        Activation of GABAB receptors (Xenopus tropicalis)
        
        Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (Xenopus tropicalis)
        
        Activation of GIRK/Kir3 Channels (Xenopus tropicalis)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Xenopus tropicalis)
        
        GABA B receptor G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Xenopus tropicalis)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Xenopus tropicalis)
        
        GABA B receptor G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
        
        GABA B receptor G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)

Signal Transduction (Xenopus tropicalis)

- Signaling by GPCR (Xenopus tropicalis)
  - GPCR downstream signalling (Xenopus tropicalis)
    - G alpha (i) signalling events (Xenopus tropicalis)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein Gi (active) [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
      - Opsins act as GEFs for G alpha-t (Xenopus tropicalis)
        
        G-alpha(t):GDP:G-beta-gamma:Opsins [plasma membrane] (Xenopus tropicalis)
        
        G-alpha(t)-GDP:G-beta-gamma [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
        
        G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Xenopus tropicalis)
        
        G-alpha(t)-GTP:G-beta-gamma [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
    - G alpha (q) signalling events (Xenopus tropicalis)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein Gq (active) [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
    - G-protein beta:gamma signalling (Xenopus tropicalis)
      - G beta:gamma signalling through PI3Kgamma (Xenopus tropicalis)
        
        G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Xenopus tropicalis)
        
        G-protein beta-gamma:PI3K gamma [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
  - GPCR ligand binding (Xenopus tropicalis)
    - Class B/2 (Secretin family receptors) (Xenopus tropicalis)
      - Glucagon-type ligand receptors (Xenopus tropicalis)
        
        GLP1R binds GLP1 (Xenopus tropicalis)
        
        GLP1:GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Xenopus tropicalis)
        
        G-beta:G-gamma (candidates) [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
        
        GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Xenopus tropicalis)
        
        G-beta:G-gamma (candidates) [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
- Signaling by WNT (Xenopus tropicalis)
  - Beta-catenin independent WNT signaling (Xenopus tropicalis)
    - Ca2+ pathway (Xenopus tropicalis)
      - 促进蛋白的核苷酸exch WNT: FZD复杂ange (Xenopus tropicalis)
        
        WNT5A/11:FZD:G-protein (alpha o/t2) active [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)
        
        WNT5A/11:FZD:G-protein (alpha o/t2) inactive [plasma membrane] (Xenopus tropicalis)
        
        Heterotrimeric G-protein (o/t2) (inactive) [plasma membrane] (Xenopus tropicalis)
        
        G-protein beta-gamma complex [plasma membrane] (Xenopus tropicalis)
        
        G-protein gamma subunit [plasma membrane] (Xenopus tropicalis)
        
        gng7 [plasma membrane] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q28H40

Gene Names

gng7

Reference Genes

BioGPS Gene:549887 gng7

ENSEMBL:ENSXETG00000026842

运用:ENSXETG00000040838 gng7

KEGG Gene (Xenopus tropicalis):549887 gng7

Monarch:549887 gng7

NCBI Gene:549887 gng7

Reference Transcript

RefSeq:NM_001017133.2 gng7

Other Identifiers

549887

GO:0003674

GO:0005575

GO:0005622

GO:0005737

GO:0005834

GO:0005886

GO:0007165

GO:0007186

GO:0008150

GO:0016020

GO:0031680

GO:0031681

GO:0032991

Str.27292.1.S1_at

Str.27292.1.S2_at

Participates

as a candidate of

Inferred From

GNG7 [plasma membrane](Homo sapiens)

Cross References

RefSeq

NP_001017133.1

Ensembl

ENSXETT00000074037,ENSXETP00000100991,ENSXETG00000040838

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