Reactome | HHF2 [nucleoplasm]

HHF2 [nucleoplasm]

Stable Identifier

R-SCE-5651656

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

Me3K21-HIST1H4, P02309

External Reference Information

External Reference

UniProt:P02309

Gene Names

HHF2

Reference Genes

BioGPS Gene:852294 HHF2

BioGPS Gene:855701 HHF2

ENSEMBL:YBR009C

KEGG Gene (Saccharomyces cerevisiae (strain YJM789)):YBR009C HHF2

KEGG Gene (Saccharomyces cerevisiae (strain YJM789)):YNL030W HHF2

Monarch:852294 HHF2

Monarch:855701 HHF2

NCBI Gene:852294 HHF2

NCBI Gene:855701 HHF2

SGD:YBR009C

Reference Transcript

Other Identifiers

1778426_s_at

852294

855701

8911_s_at

GO:0000786

GO:0000788

GO:0003674

GO:0003677

GO:0005575

GO:0005634

GO:0005694

GO:0006325

GO:0006333

GO:0006334

GO:0006366

GO:0008150

GO:0008213

GO:0016570

GO:0018193

GO:0031298

GO:0034729

: 0042393

GO:0043934

GO:0043935

GO:0046982

GO:0051321

GO:0061587

Other forms of this molecule

HHF2 [nucleoplasm]

Inferred From

Me3K21-HIST1H4 [nucleoplasm](Homo sapiens)

Modified Residues

Name

N6,N6,N6-trimethyl-L-lysine at 21 (in Homo sapiens)

Coordinate

PsiMod Name

N6,N6,N6-trimethyl-L-lysine [MOD:00083]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6,N6,N6-trimethyl-L-lysine.

Cross References

RefSeq

NP_009563.1,NP_014368.1

PRO

P02309

PDB

Interactors (64)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61830	11	HHT2 [nucleoplasm](r -CE-427504) HHT2 [nucleoplasm](r -CE-427369) HHT2 [nucleoplasm](r -CE-5250654) HHT2 [nucleoplasm](r -CE-5625747) HHT2 [nucleoplasm](r -CE-5625800) phospho-HHT2 [nucleoplasm](r -CE-5625758) HHT2 [nucleoplasm](r -CE-427324) HHT2 [nucleoplasm](r -CE-1214216) HHT2 [nucleoplasm](r -CE-212295) HHT2 [nucleoplasm](r -CE-1214206) HHT2 [nucleoplasm](r -CE-212282)	0.912	69
UniProt:P04912	52	HTA2 [nucleoplasm](r -CE-6782493-2) HTA2 [nucleoplasm](r -CE-6782532-2) HTA2 [nucleoplasm](r -CE-6782514-2) HTA2 [nucleoplasm](r -CE-6782531-2) HTA2 [nucleoplasm](r -CE-4568572-2) HTA2 [nucleoplasm](r -CE-4568611-2) HTA2 [nucleoplasm](r -CE-4568583-2) HTA2 [nucleoplasm](r -CE-4568598-2) HTA2 [nucleoplasm](r -CE-4551321-2) HTA2 [nucleoplasm](r -CE-4551333-2) HTA2 [nucleoplasm](r -CE-4551338-2) HTA2 [nucleoplasm](r -CE-4551332-2) HTA2 [nucleoplasm](r -CE-5244584-2) HTA2 [nucleoplasm](r -CE-5244581-2) HTA2 [nucleoplasm](r - sce - 5244538 - 2) HTA2 [nucleoplasm](r -CE-5244562-2) HTA2 [nucleoplasm](r -CE-5244557-2) HTA2 [nucleoplasm](r -CE-5244574-2) HTA2 [nucleoplasm](r -CE-5244542-2) HTA2 [nucleoplasm](r -CE-5244576-2) HTA2 [nucleoplasm](r -CE-5244590-2) HTA2 [nucleoplasm](r -CE-5244621-2) HTA2 [nucleoplasm](r -CE-5244589-2) HTA2 [nucleoplasm](r -CE-5244628-2) HTA2 [nucleoplasm](r -CE-5244612-2) phospho-HTA2 [nucleoplasm](r -CE-5682847-2) phospho-HTA2 [nucleoplasm](r -CE-75170-2) phospho-HTA2 [nucleoplasm](r -CE-5683953-2) phospho-HTA2 [nucleoplasm](r -CE-5683942-2) HTA2 [nucleoplasm](r -CE-56151-2) HTA2 [nucleoplasm](r -CE-181890-2) HTA2 [nucleoplasm](r -CE-181888-2) HTA2 [nucleoplasm](r -CE-181892-2) HTA2 [nucleoplasm](r -CE-181887-2) HTA2 [nucleoplasm](r - sce - 4549203 - 2) HTA2 [nucleoplasm](r -CE-5229231-2) HTA2 [nucleoplasm](r -CE-5229221-2) HTA2 [nucleoplasm](r -CE-5229202-2) HTA2 [nucleoplasm](r -CE-5229227-2) HTA2 [nucleoplasm](r -CE-5229308-2) HTA2 [nucleoplasm](r -CE-5229306-2) HTA2 [nucleoplasm](r -CE-5229297-2) HTA2 [nucleoplasm](r -CE-5229310-2) HTA2 [nucleoplasm](r -CE-5218317-2) HTA2 [nucleoplasm](r -CE-5218304-2) HTA2 [nucleoplasm](r -CE-5229211-2) HTA2 [nucleoplasm](r -CE-5218314-2) HTA2 [nucleoplasm](r -CE-5218311-2) HTA2 [nucleoplasm](r -CE-5218305-2) HTA2 [nucleoplasm](r -CE-5244595-2) HTA2 [nucleoplasm](r -CE-5244625-2) HTA2 [nucleoplasm](r -CE-5244606-2)	0.793	18
UniProt:Q12373 HIF1			0.752	23
UniProt:P32447	1	ASF1 [nucleoplasm](r -CE-417169)	0.752	18
UniProt:Q12161 PSH1			0.744	17
UniProt:Q06205 FKBP4			0.678	5
UniProt:P02309	14	HHF2 [nucleoplasm](r -CE-212078) HHF2 [nucleoplasm](r -CE-4570518) HHF2 [nucleoplasm](r -CE-4568744) HHF2 [nucleoplasm](r -CE-4568748) HHF2 [nucleoplasm](r -CE-427469) HHF2 [nucleoplasm](r -CE-4568758) HHF2 [nucleoplasm](r -CE-5229015) HHF2 [nucleoplasm](r -CE-4754243) HHF2 [nucleoplasm](r -CE-4754240) HHF2 [nucleoplasm](r -CE-5651656) HHF2 [nucleoplasm](r -CE-3451124) HHF2 [nucleoplasm](r -CE-2172676) HHF2 [nucleoplasm](r -CE-181902) HHF2 [nucleoplasm](r -CE-5651652)	0.678	7
UniProt:P32597	1	STH1 [nucleoplasm](r -CE-389256-2)	0.677	4
UniProt:P02293	17	HTB1 [nucleoplasm](r -CE-6782554) HTB1 [nucleoplasm](r -CE-6782561) HTB1 [nucleoplasm](r -CE-181898) HTB1 [nucleoplasm](r -CE-181916) HTB1 [nucleoplasm](r -CE-3364019) HTB1 [nucleoplasm](r -CE-3364020) HTB1 [nucleoplasm](r -CE-4568637) HTB1 [nucleoplasm](r -CE-4568639) HTB1 [nucleoplasm](r -CE-4568629) HTB1 [nucleoplasm](r -CE-4568632) HTB1 [nucleoplasm](r -CE-4568660) HTB1 [nucleoplasm](r -CE-4568647) HTB1 [nucleoplasm](r -CE-4568631) HTB1 [nucleoplasm](r -CE-4568615) HTB1 [nucleoplasm](r -CE-4568624) HTB1 [nucleoplasm](r -CE-4549272) HTB1 [nucleoplasm](r - sce - 4549263)	0.669	3
UniProt:Q04636	1	POB3 [nucleoplasm](r -CE-65105)	0.669	10
UniProt:P40161 RT106			0.669	8
UniProt:P15790 CKA1	5	CKA1 [nucleoplasm](r -CE-6805057) CKA1 [nucleoplasm](r -CE-6790643) CKA1 [nucleoplasm](r -CE-6805065) CKA1 [cytosol](r -CE-201721) CKA1 [cytosol](r -CE-201713)	0.669	3
UniProt:P39984	1	HAT2 [nucleoplasm](r -CE-212227-2)	0.669	15
UniProt:P32558	1	SPT16 [nucleoplasm](r -CE-112415)	0.669	16
UniProt:Q12341	1	HAT1 [nucleoplasm](r -CE-3662337)	0.669	27
UniProt:P11746	2	MCM1 [nucleoplasm](r -CE-5666000) phospho-MCM1 [nucleoplasm](r -CE-9612518)	0.669	3
UniProt:Q08649	5	ESA1 [nucleoplasm](r -CE-5603260) ESA1 [nucleoplasm](r -CE-3321823) ESA1 [nucleoplasm](r -CE-3318400) phospho-ESA1 [nucleoplasm](r -CE-6805633) ESA1 [nucleoplasm](r -CE-480310)	0.667	5
UniProt:Q02486	2	ABF2 [nucleoplasm](r -CE-266211-3) ABF2 [mitochondrial matrix](r -CE-163312-3)	0.628	8
UniProt:Q00362	1	CDC55 [cytosol](r -CE-377253)	0.592	4
UniProt:P38890	1	SET5 [nucleoplasm](r -CE-3222233)	0.59	3
UniProt:P47050	2	RTT101 [nucleoplasm](r -CE-976006) RTT101 [nucleoplasm](r -CE-975973)	0.589	2
UniProt:Q03973	2	HMO1 [nucleoplasm](r -CE-266211-5) HMO1 [mitochondrial matrix](r -CE-163312-5)	0.564	3
UniProt:P02294	17	HTB2 [nucleoplasm](r -CE-6782554-2) HTB2 [nucleoplasm](r -CE-6782561-2) HTB2 [nucleoplasm](r -CE-4549263-2) HTB2 [nucleoplasm](r -CE-4549272-2) HTB2 [nucleoplasm](r -CE-4568624-2) HTB2 [nucleoplasm](r -CE-4568615-2) HTB2 [nucleoplasm](r -CE-4568631-2) HTB2 [nucleoplasm](r -CE-4568647-2) HTB2 [nucleoplasm](r -CE-4568660-2) HTB2 [nucleoplasm](r -CE-4568632-2) HTB2 [nucleoplasm](r -CE-4568629-2) HTB2 [nucleoplasm](r -CE-4568639-2) HTB2 [nucleoplasm](r -CE-4568637-2) HTB2 [nucleoplasm](r -CE-3364020-2) HTB2 [nucleoplasm](r -CE-3364019-2) HTB2 [nucleoplasm](r -CE-181916-2) HTB2 [nucleoplasm](r -CE-181898-2)	0.564	8
UniProt:P32833	1	ORC2 [nucleoplasm](r -CE-68405)	0.564	2
UniProt:P36124	1	SET3 [nucleoplasm](r -CE-1183225)	0.564	2
UniProt:P38826 ORC6			0.564	2
UniProt:P54784	4	phospho-ORC1 [cytosol](r -CE-9032195) phospho-ORC1 [nucleoplasm](r -CE-68943) phospho-ORC1 [nucleoplasm](r -CE-9032189) ORC1 [nucleoplasm](r -CE-68522)	0.564	2
UniProt:Q12510 CMR1			0.564	2
UniProt:Q9Y294 ASF1A	1	ASF1A [nucleoplasm](R-HSA-417169)	0.556	3
UniProt:P32333 MOT1			0.527	2
UniProt:P31244 RAD16			0.527	3
UniProt:P33748 MSN2			0.527	2
UniProt:Q06488	1	RSC2 [nucleoplasm](r -CE-389254)	0.527	2
UniProt:P32657 CHD1			0.527	2
UniProt:Q01477 UBP3			0.527	2
UniProt:Q04199 CAC2			0.527	3
UniProt:P53741 BRE5			0.527	2
UniProt:P43639 CKB1	1	CKB1 [nucleoplasm](r -CE-6790659)	0.527	2
UniProt:Q03940	1	RVB1 [nucleoplasm](r -CE-418323)	0.527	2
UniProt:P43596 IOC3			0.527	2
UniProt:Q12692	3	HTZ1 [nucleoplasm](r -CE-8862427) HTZ1 [nucleoplasm](r -CE-5218308) HTZ1 [nucleoplasm](r -CE-181897)	0.527	4
UniProt:P05317	1	RPP0 [cytosol](r -CE-72396)	0.527	3
UniProt:P53091 MCM6	2	MCM6 [nucleoplasm](r -CE-68553) yMcm6 [nucleoplasm](r -CE-169504)	0.527	2
UniProt:P43609	2	RSC8 [nucleoplasm](r -CE-389263-2) RSC8 [nucleoplasm](r -CE-389257)	0.527	2
UniProt:P34218	1	SAS3 [nucleoplasm](r -CE-3321979)	0.527	3
UniProt:P11938 RAP1			0.527	3
UniProt:P46677	2	TAF1 [nucleoplasm](r -CE-65539) TAF1 [nucleoplasm](r -CE-212435)	0.527	2
UniProt:Q12464 RUVB2			0.527	2
UniProt:P38144 ISW1			0.527	2
UniProt:P32481 GCD11	2	GCD11 [cytosol](r -CE-72514) GCD11 [cytosol](r -CE-9633596)	0.527	2
UniProt:P14832 CYPH			0.527	2
UniProt:P40069 IMB4			0.527	3
UniProt:P10592	8	SSA2 [nucleoplasm](r -CE-5082380) SSA2 [cytosol](r -CE-264476) SSA2 [ficolin-1-rich granule lumen](r -CE-6801494) SSA2 [extracellular region](r -CE-6805936) SSA2 [secretory granule lumen](r -CE-6801530) SSA2 [nucleoplasm](r -CE-912480-3) SSA2 [cytosol](r -CE-3371408-3) SSA2 [nucleoplasm](r -CE-8932217)	0.527	3
UniProt:Q06639 RSC3			0.527	4
UniProt:P11484 SSB1			0.527	3
UniProt:Q04779 RCO1			0.527	2
UniProt:Q03761	1	TAF12 [nucleoplasm](r -CE-65555)	0.527	2
UniProt:P43572 EPL1			0.527	2
UniProt:P22579	3	SIN3 [nucleoplasm](r -CE-351657) SIN3 [nucleoplasm](r -CE-4086071) SIN3 [nucleoplasm](r -CE-349685)	0.527	2
UniProt:Q12432 EAF3			0.527	2
UniProt:P29496 MCM5	2	yMcm5 [nucleoplasm](r -CE-169511) MCM5 [nucleoplasm](r -CE-68551)	0.527	3
UniProt:P36012	43	CSE4 [nucleoplasm](r -CE-4551293) CSE4 [nucleoplasm](r -CE-427507) CSE4 [nucleoplasm](r -CE-4551291) CSE4 [nucleoplasm](r -CE-4551292) CSE4 [nucleoplasm](r -CE-4568754) CSE4 [nucleoplasm](r -CE-4568761) CSE4 [nucleoplasm](r -CE-4568751) CSE4 [nucleoplasm](r -CE-4549217) CSE4 [nucleoplasm](r -CE-5229052) CSE4 [nucleoplasm](r -CE-5229062) CSE4 [nucleoplasm](r -CE-5211328) CSE4 [nucleoplasm](r -CE-5218935) CSE4 [nucleoplasm](r -CE-4754193) CSE4 [nucleoplasm](r -CE-4722135) CSE4 [nucleoplasm](r -CE-5649791) CSE4 [nucleoplasm](r -CE-5649795) CSE4 [nucleoplasm](r -CE-5649768) CSE4 [nucleoplasm](r -CE-5638160) CSE4 [nucleoplasm](r -CE-4722125) CSE4 [nucleoplasm](r -CE-212105) CSE4 [nucleoplasm](r -CE-5638327) CSE4 [cytosol](r -CE-8943830) CSE4 [cytosol](r -CE-8943831) CSE4 [nucleoplasm](r -CE-5244526) CSE4 [nucleoplasm](r -CE-4687016) CSE4 [nucleoplasm](r -CE-5246532) CSE4 [nucleoplasm](r -CE-181914) CSE4 [nucleoplasm](r -CE-1214170) CSE4 [nucleoplasm](r -CE-212253) CSE4 [nucleoplasm](r -CE-1214186) CSE4 [nucleoplasm](r -CE-427378) phospho-CSE4 [nucleoplasm](r -CE-5625757) phospho-CSE4 [nucleoplasm](r -CE-5625790) CSE4 [nucleoplasm](r -CE-427734) CSE4 [nucleoplasm](r - sce - 4568924) CSE4 [nucleoplasm](r -CE-4568939) CSE4 [nucleoplasm](r -CE-5244806) CSE4 [nucleoplasm](r -CE-5244801) CSE4 [nucleoplasm](r -CE-5244529) CSE4 [nucleoplasm](r -CE-5229059) CSE4 [nucleoplasm](r -CE-5246534) CSE4 [nucleoplasm](r -CE-5246530) CSE4 [nucleoplasm](r -CE-5246544)	0.524	2
UniProt:Q05123	1	ARP9 [nucleoplasm](r -CE-2980912-2)	0.508	2
UniProt:P37898	5	AAP1 [secretory granule membrane](r -CE-6806152-2) AAP1 [plasma membrane](r -CE-2022340-2) AAP1 [cytosol](r -CE-983098-2) AAP1 [endoplasmic reticulum lumen](r -CE-947609-2) AAP1 [endoplasmic reticulum lumen](r -CE-983097-2)	0.508	2

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