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UBA52(1-76) [endosome membrane]
Stable Identifier
R-HSA-939189
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endosome membrane
Synonyms
UBA52, ubiquitin (UBA52)
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Assembly Of The HIV Virion (Homo sapiens)
Synthesis And Processing Of GAG, GAGPOL Polyproteins (Homo sapiens)
Membrane binding and targetting of GAG proteins (Homo sapiens)
Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex (Homo sapiens)
monoubiquitinated N-myristoyl GAG (P04591) protein [endosome membrane] (Homo sapiens)
ubiquitin [endosome membrane] (Homo sapiens)
UBA52(1-76) [endosome membrane] (Homo sapiens)
Transport of GAG to the Plasma Membrane (Homo sapiens)
monoubiquitinated N-myristoyl GAG (P04591) protein [endosome membrane] (Homo sapiens)
ubiquitin [endosome membrane] (Homo sapiens)
UBA52(1-76) [endosome membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Endosomal Sorting Complex Required For Transport (ESCRT) (Homo sapiens)
Cargo Recognition And Sorting (Homo sapiens)
ESCRT-0/Cargo Complex [endosome membrane] (Homo sapiens)
Ubiquinated and PIP3 Endosmal Membrane Bound Cargo [endosome membrane] (Homo sapiens)
ubiquitin [endosome membrane] (Homo sapiens)
UBA52(1-76) [endosome membrane] (Homo sapiens)
ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
Ubiquinated and PIP3 Endosmal Membrane Bound Cargo [endosome membrane] (Homo sapiens)
ubiquitin [endosome membrane] (Homo sapiens)
UBA52(1-76) [endosome membrane] (Homo sapiens)
Cargo Sequestration (Homo sapiens)
ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
Ubiquinated and PIP3 Endosmal Membrane Bound Cargo [endosome membrane] (Homo sapiens)
ubiquitin [endosome membrane] (Homo sapiens)
UBA52(1-76) [endosome membrane] (Homo sapiens)
ESCRT-II/Cargo Complex [endosome membrane] (Homo sapiens)
Ubiquinated and PIP3 Endosmal Membrane Bound Cargo [endosome membrane] (Homo sapiens)
ubiquitin [endosome membrane] (Homo sapiens)
UBA52(1-76) [endosome membrane] (Homo sapiens)
ESCRT Disassembly (Homo sapiens)
ESCRT-III/Cargo Complex [endosome membrane] (Homo sapiens)
Ubiquinated and PIP3 Endosmal Membrane Bound Cargo [endosome membrane] (Homo sapiens)
ubiquitin [endosome membrane] (Homo sapiens)
UBA52(1-76) [endosome membrane] (Homo sapiens)
MVB Vesicle Formation (Homo sapiens)
ESCRT-II/Cargo Complex [endosome membrane] (Homo sapiens)
Ubiquinated and PIP3 Endosmal Membrane Bound Cargo [endosome membrane] (Homo sapiens)
ubiquitin [endosome membrane] (Homo sapiens)
UBA52(1-76) [endosome membrane] (Homo sapiens)
ESCRT-III/Cargo Complex [endosome membrane] (Homo sapiens)
Ubiquinated and PIP3 Endosmal Membrane Bound Cargo [endosome membrane] (Homo sapiens)
ubiquitin [endosome membrane] (Homo sapiens)
UBA52(1-76) [endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P62987 UBA52
Gene Names
UBA52, UBCEP2
Chain
chain:1-76, chain:77-128
Reference Genes
BioGPS Gene:7311 UBA52
COSMIC (genes):UBA52 UBA52
CTD Gene:7311 UBA52
dbSNP Gene:7311 UBA52
ENSEMBL:ENSG00000221983 UBA52
HGNC:12458 UBA52
KEGG Gene (Homo sapiens):7311 UBA52
Monarch:7311 UBA52
NCBI Gene:7311 UBA52
OMIM:191321 UBA52
Reference Transcript
RefSeq:NM_001033930.2 UBA52
RefSeq:NM_001321020.1 UBA52
RefSeq:NM_003333.4 UBA52
RefSeq:NM_001321018.1 UBA52
RefSeq:NM_001321017.1 UBA52
RefSeq:NM_001321019.1 UBA52
Other Identifiers
0004920441
11729104_x_at
11756215_x_at
16859825
221700_s_at
3476750
3537801
3825202
3825203
3825204
3825206
3825207
3825208
3825209
3825210
3825212
3825214
3825216
3825217
3825218
3825219
3825220
3825221
3825222
3825224
58604_s_at
7311
8027024
A_23_P56188
A_23_P56195
A_24_P173325
A_24_P65779
GE79164
GE85590
GE85604
GO:0000122
GO:0000184
GO:0000187
GO:0000209
GO:0000278
GO:0000715
GO:0000717
GO:0002181
GO:0002753
GO:0002755
GO:0002756
GO:0003674
GO:0003735
GO:0005198
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005741
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005783
GO:0005789
GO:0005829
GO:0005840
GO:0005886
GO:0006259
GO:0006283
去:0006294
GO:0006296
去:0006297
GO:0006364
GO:0006412
GO:0006413
GO:0006464
GO:0006605
GO:0006614
GO:0006810
GO:0006914
GO:0006950
GO:0007049
GO:0007096
GO:0007165
GO:0007179
GO:0007249
GO:0007254
去:0007267
GO:0008104
GO:0008150
GO:0008219
GO:0009056
GO:0009058
GO:0010008
GO:0015031
GO:0016055
GO:0016192
GO:0016197
GO:0016567
GO:0016579
GO:0017085
GO:0019058
GO:0019068
GO:0019081
GO:0019083
GO:0019221
GO:0019899
GO:0019941
GO:0019985
GO:0022607
GO:0022625
GO:0022626
GO:0022627
GO:0030512
GO:0030666
GO:0031145
GO:0031386
GO:0031410
GO:0031625
GO:0031982
GO:0032991
GO:0033683
GO:0034641
GO:0034655
GO:0035666
GO:0035973
GO:0036297
GO:0036388
GO:0042254
GO:0042276
GO:0042769
GO:0043065
GO:0043066
GO:0043226
GO:0043488
GO:0043657
去:0044322
GO:0044403
GO:0045944
GO:0051092
GO:0051276
GO:0051403
GO:0052031
GO:0055085
GO:0061024
GO:0061418
GO:0065003
GO:0070062
GO:0070423
GO:0070498
GO:0070911
GO:0070987
GO:0075733
GO:0140014
GO:1904380
GO:1990000
HMNXSV003054363
ILMN_1782977
ILMN_2368576
PH_hs_0028727
PH_hs_0037046
TC19000360.hg
X56997_rna1_at
g13569611_3p_s_at
Participates
as a member of
ubiquitin [endosome membrane] (Homo sapiens)
Other forms of this molecule
UBA52(1-76) [endocytic vesicle membrane]
Ub-33-UBA52(1-76) [mitochondrial outer membrane]
Ub-63-UBA52(1-76) [mitochondrial outer membrane]
Ub-6-UBA52(1-76) [mitochondrial outer membrane]
Ub-11-UBA52(1-76) [mitochondrial outer membrane]
Ub-48-UBA52(1-76) [mitochondrial outer membrane]
Ub-29-UBA52(1-76) [mitochondrial outer membrane]
Ub-27-UBA52(1-76) [mitochondrial outer membrane]
N6-glycyl-L-lysine-UBA52(1-76) [cytosol]
adenylatedG76-UBA52(1-76) [nucleoplasm]
UBA52(1-128) [cytosol]
adenylatedG76-UBA52(1-76) [cytosol]
Ub-48-UBA52(1-76) [endoplasmic reticulum membrane]
UBA52(1-76) [plasma membrane]
UBA52(1-76) [endoplasmic reticulum membrane]
Ub-29-UBA52(1-76) [cytosol]
Ub-11-UBA52(1-76) [cytosol]
Ub-6-UBA52(1-76) [cytosol]
Ub-33-UBA52(1-76) [cytosol]
Ub-27-UBA52(1-76) [cytosol]
RPL40 [cytosol]
Ub-63-UBA52(1-76) [endosome membrane]
Ub-63-UBA52(1-76) [plasma membrane]
Ub-27-UBA52(1-76) [nucleoplasm]
Ub-29-UBA52(1-76) [nucleoplasm]
Ub-48-UBA52(1-76) [nucleoplasm]
Ub-11-UBA52(1-76) [nucleoplasm]
Ub-33-UBA52(1-76) [nucleoplasm]
UBA52(1-76) [nucleoplasm]
Ub-48-UBA52(1-76) [nucleoplasm]
Ub-63-UBA52(1-76) [nucleoplasm]
Ub-6-UBA52(1-76) [nucleoplasm]
UBA52(1-76) [late endosome lumen]
Ub-48-UBA52(1-76) [cytosol]
UBA52(1-76) [cytosol]
UBA52(1-76) [lysosomal lumen]
Ub-63-UBA52(1-76) [cytosol]
Inferred To
UBB(核内体膜)
(Gallus gallus)
Uba52 [endosome membrane]
(Mus musculus)
Uba52 [endosome membrane]
(Rattus norvegicus)
UBA52 [endosome membrane]
(Bos taurus)
UBA52 [endosome membrane]
(Canis familiaris)
UBA52 [endosome membrane]
(Sus scrofa)
ubc [endosome membrane]
(Xenopus tropicalis)
RPL40B [endosome membrane]
(Saccharomyces cerevisiae)
nedd8l1 [endosome membrane]
(Dictyostelium discoideum)
ubq-1 [endosome membrane]
(Caenorhabditis elegans)
RpL40 [endosome membrane]
(Drosophila melanogaster)
ubi3 [endosome membrane]
(Schizosaccharomyces pombe)
uep1 [endosome membrane]
(Schizosaccharomyces pombe)
RPL40A [endosome membrane]
(Saccharomyces cerevisiae)
Homologues of RPS27A(1-76) [endosome membrane]
(Saccharomyces cerevisiae)
Homologues of RPS27A(1-76) [endosome membrane]
(Schizosaccharomyces pombe)
ubi1 [endosome membrane]
(Schizosaccharomyces pombe)
RPS31 [endosome membrane]
(Saccharomyces cerevisiae)
uba52 [endosome membrane]
(Danio rerio)
ubi5 [endosome membrane]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_003324.1
,
NP_001307949.1
,
NP_001307947.1
,
NP_001029102.1
,
NP_001307948.1
,
NP_001307946.1
OpenTargets
ENSG00000221983
HPA
ENSG00000221983-UBA52
GeneCards
P62987
Ensembl
ENSP00000388107
,
ENST00000595683
,
ENSG00000221983
,
ENSP00000473048
,
ENSP00000472264
,
ENST00000598780
,
ENST00000599595
,
ENST00000442744
,
ENSP00000471062
,
ENSP00000396910
,
ENST00000599551
,
ENSP00000471464
,
ENST00000597451
,
ENST00000596273
,
ENST00000596304
,
ENSP00000470507
,
ENSP00000470419
,
ENST00000430157
,
ENSP00000472545
,
ENSP00000471622
,
ENST00000595158
PRO
P62987
Pharos - Targets
P62987
GlyGen
P62987
PDB
5GOB
,
5GOK
,
6Z6M
,
6IP6
,
5JBY
,
5HPT
,
6OLF
,
6Y6X
,
6OLG
,
2NBE
,
5HPL
,
6Y57
,
5GOI
,
5J8P
,
4PIJ
,
5HPS
,
6OM7
,
5AJ0
,
4S1Z
,
5GO8
,
4PIH
,
6ZMO
,
6OLE
,
6OLZ
,
4XKL
,
4V6X
,
2NBD
,
5GO7
,
2N3U
,
5LKS
,
2N3V
,
5T2C
,
6IP8
,
2RSU
,
6Z6N
,
4JIO
,
6XA1
,
6OLI
,
6EK0
,
6IP5
,
6ZM7
,
4HJK
,
5JBV
,
6Z6L
,
2MJB
,
6QZP
,
2MBH
,
4UG0
,
5GOJ
,
5GOG
,
6Y0G
,
6OM0
,
2MUR
,
4 p4h
,
6ZMI
,
2N3W
,
6Y2L
,
4PIG
,
5GOH
,
5HPK
,
4RF0
,
5GOD
,
5J26
,
6ZME
,
5GOC
,
4RF1
,
2LJ5
,
6LQM
Interactors (18)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y3C5 RNF11
0.666
4
UniProt:Q15038 DAZP2
0.666
7
UniProt:Q6ICB0 DESI1
0.601
4
UniProt:Q9UMX0 UBQLN1
1
UBQLN1 [cytosol]
(R-HSA-8866006)
0.556
3
UniProt:O95208-2 EPN2
0.556
3
UniProt:Q9UJ41-4 RABGEF1
0.556
3
UniProt:Q99732 LITAF
0.556
3
UniProt:Q9NRQ2 PLS4
0.556
3
UniProt:Q9UHD9 UBQLN2
1
UBQLN2 [cytosol]
(R-HSA-8866007)
0.556
3
UniProt:P54725 RAD23A
1
RAD23A [nucleoplasm]
(R-HSA-5688076)
0.556
3
UniProt:Q8N3F0 MTURN
0.556
3
UniProt:Q96CS7 PKHB2
0.556
3
UniProt:Q92567-2 FAM168A
0.556
3
UniProt:Q86VP1 TAX1BP1
1
TAX1BP1 [cytosol]
(R-HSA-937346)
0.556
3
UniProt:Q96B67 ARRD3
0.556
3
UniProt:Q14203-5 DCTN1
0.556
3
UniProt:P37840 SNCA
4
SNCA [extracellular region]
(R-HSA-976954)
SNCA A30P [cytosol]
(R-HSA-5658569)
SNCA [cytosol]
(R-HSA-5658500)
Ub-SNCA [cytosol]
(R-HSA-5660754)
0.556
3
UniProt:P63244 RACK1
1
GNB2L1 [cytosol]
(R-HSA-5626956)
0.495
2
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