Reactome | CAPZA1(265-276) [extracellular region]

CAPZA1(265-276) [extracellular region]

Stable Identifier

R-HSA-879421

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

F-actin-capping protein subunit alpha-1 fragment TRTK-12, TRTK-12, CAPZA1, CAZA1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P52907 CAPZA1

Gene Names

CAPZA1

Chain

initiator methionine:1, chain:2-286

Reference Genes

BioGPS Gene:829 CAPZA1

COSMIC (genes):CAPZA1 CAPZA1

CTD Gene:829 CAPZA1

dbSNP Gene:829 CAPZA1

ENSEMBL:ENSG00000116489 CAPZA1

HGNC:1488 CAPZA1

KEGG Gene (Homo sapiens):829 CAPZA1

Monarch:829 CAPZA1

NCBI Gene:829 CAPZA1

OMIM:601580 CAPZA1

UCSC:P52907 CAPZA1

Reference Transcript

RefSeq:NM_006135.2 CAPZA1

Other Identifiers

0002570020

11739005_at

11739006_x_at

11739007_at

11739008_x_at

208374_s_at

2352235

2352236

2352248

2352249

2352253

2352255

2352257

2352260

2352264

2352265

2352267

2352268

2352269

2352274

40910_at

74743_f_at

7904036

829

A_24_P310894

A_24_P379379

GE62127

GO:0002376

GO:0003674

GO:0003779

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005829

GO:0005856

去:0006810

GO:0006888

GO:0006950

去:0007010

GO:0007165

GO:0007596

GO:0008092

GO:0008150

GO:0008290

GO:0015629

GO:0016192

GO:0019886

GO:0022607

GO:0030036

GO:0030479

GO:0032991

GO:0034329

GO:0034330

GO:0035722

GO:0043226

GO:0045087

GO:0045296

GO:0051015

GO:0051016

GO:0051693

GO:0065003

GO:0070062

GO:0071203

HMNXSV003044708

Hs.247811.0.S1_3p_s_at

PH_hs_0029720

TC01000990.hg

TC01004629.hg

U56637_at

g5453596_3p_a_at

Participates

as a member of

F-actin capping protein alpha protein fragment TRTK-12 [extracellular region] (Homo sapiens)

Other forms of this molecule

CAPZA1 [cytosol]

Inferred To

cap-1 [extracellular region](Caenorhabditis elegans)

acp1 [extracellular region](Schizosaccharomyces pombe)

capza1 [extracellular region](Xenopus tropicalis)

Capza1 [extracellular region](Mus musculus)

Capza1 [extracellular region](鼠形)

acpB [extracellular region](Dictyostelium discoideum)

capza1b [extracellular region](Danio rerio)

CAP1 [extracellular region](Saccharomyces cerevisiae)

CAPZA1(265-276) [extracellular region](Plasmodium falciparum)

CAPZA1 [extracellular region](Canis familiaris)

CAPZA1 [extracellular region](Gallus gallus)

CAPZA1 [extracellular region](Sus scrofa)

cpa [extracellular region](Drosophila melanogaster)

Cross References

RefSeq

NP_006126.1

OpenTargets

ENSG00000116489

HPA

ENSG00000116489-CAPZA1

GeneCards

P52907

Ensembl

ENSG00000116489,ENSP00000263168,ENST00000263168

PRO

P52907

Pharos - Targets

P52907

GlyGen

P52907

PDB

1 mwn,1MQ1

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96B97 SH3KBP1	3	SH3KBP1 [cytosol](R-HSA-182957) SH3KBP1 [plasma membrane](R-HSA-182955) Ub-SH3KBP1 [cytosol](R-HSA-182926)	0.708	5
UniProt:P04271 S100B	1	S100B [extracellular region](R-HSA-879433)	0.611	3
UniProt:P23297 S100A1	1	S100A1 [extracellular region](R-HSA-6805991)	0.544	2
UniProt:P33763 S10A5			0.544	2
UniProt:P25815 S100P	2	S100P [secretory granule lumen](R-HSA-6804782) S100P [extracellular region](R-HSA-6804809)	0.544	2
UniProt:P47755 CAPZA2	2	CAPZA2 [cytosol](R-HSA-879448) CAPZA2(265-276) [extracellular region](r - hsa - 879417)	0.527	2
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane](R-HSA-197834)	0.527	4
UniProt:Q13561 DCTN2	1	DCTN2 [cytosol](R-HSA-380302)	0.508	2
UniProt:Q14203 DCTN1	7	DCTN1(1-599)-ALK(1058-1620) fusion [cytosol](R-HSA-9711960) DCTN1(1-1065)-ALK(1058-1620) fusion [cytosol](R-HSA-9711969) DCTN1(1-1177)-ALK(1058-1620) fusion [cytosol](R-HSA-9701997) DCTN1(1-1065)-p-7Y ALK(1058-1620) fusion [cytosol](R-HSA-9711959) DCTN1(1-599)-p-7Y ALK(1058-1620) fusion [cytosol](R-HSA-9711953) DCTN1(1-1177)-p-7Y ALK(1058-1620) fusion [cytosol](R-HSA-9711962) DCTN1 [cytosol](R-HSA-535580)	0.508	2
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [ChEBI:16851]	7	PI(3,5)P2 [plasma membrane](R-ALL-1806224) PI(3,5)P2 [phagophore assembly site membrane](R-ALL-5692959) PI(3,5)P2 [Golgi membrane](R-ALL-1806290) PI(3,5)P2 [early endosome membrane](R-ALL-1806205) PI(3,5)P2 [late endosome membrane](R-ALL-1806289) PI(3,5)P2 [endoplasmic reticulum membrane](R-ALL-6809774) PI(3,5)P2 [lysosomal membrane](R-ALL-5334668)	0.462	2
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [ChEBI:18348]	6	PI(4,5)P2 [Golgi membrane](R-ALL-1806165) PI(4,5)P2 [plasma membrane](R-ALL-179856) PI(4,5)P2 [endoplasmic reticulum membrane](R-ALL-2023856) PI(4,5)P2 [nucleoplasm](R-ALL-6810412) PI(4,5)P2 [cytoplasmic vesicle membrane](R-ALL-8874467) PI(4,5)P2 [early endosome membrane](R-ALL-8849966)	0.462	2

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