Reactome | p-T714,T734-BARD1[核质]

p-T714, T734-BARD1(核浆)

稳定的标识符

r - hsa - 5659846

类型

蛋白质(EntityWithAccessionedSequence)

物种

智人

室

核浆

图标

路径浏览器中的位置

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细胞周期(智人)

- 细胞周期检查点(人类)
  - G2/M检查点(人类)
    - G2/M DNA损伤检查点(人类)
      - ATR使TP53磷酸化(智人)
        
        ATR:ATRIP:RPA:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
      - CHEK2被招募到DNA DSBs(智人)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A复合物[核质](智人)
        
        p-4S,2T-BRCA1-A复合体[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex:CHEK2[核质](智人)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A复合物[核质](智人)
        
        p-4S,2T-BRCA1-A复合体[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
      - ATM对CHEK2的磷酸化和激活(人类)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A复合物[核质](智人)
        
        p-4S,2T-BRCA1-A复合体[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex:CHEK2[核质](智人)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A复合物[核质](智人)
        
        p-4S,2T-BRCA1-A复合体[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)

DNA修复(人类)

- DNA双链断裂修复(人类)
  - DNA双链断裂反应(人类)
    - DNA双链断裂修复和信号蛋白的募集和atm介导的磷酸化(人类)
      - CHEK2被招募到DNA DSBs(智人)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A复合物[核质](智人)
        
        p-4S,2T-BRCA1-A复合体[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex:CHEK2[核质](智人)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A复合物[核质](智人)
        
        p-4S,2T-BRCA1-A复合体[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
      - CHEK2磷酸化BRCA1(人类)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A复合物[核质](智人)
        
        p-4S,2T-BRCA1-A复合体[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-5S,2T-BRCA1-A复合物[核质](智人)
        
        p-5S,2T-BRCA1-A复合物[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
      - ATM对CHEK2的磷酸化和激活(人类)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A复合物[核质](智人)
        
        p-4S,2T-BRCA1-A复合体[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A complex:CHEK2[核质](智人)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A复合物[核质](智人)
        
        p-4S,2T-BRCA1-A复合体[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
      - ATM在多个位点磷酸化BRCA1-A复合物(现代人)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A复合物[核质](智人)
        
        p-4S,2T-BRCA1-A复合体[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-S1387,S1423,S1524,S1547-BRCA1:p-T714,T734-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
  - 同源定向修复(人类)
    - HDR通过同源重组(HRR)或单链退火(SSA)(智人)
      - HDR通过同源重组(HRR)(智人)
        
        DNA聚合酶的d -环延伸(人类)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3复合物[核质](智人)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3复合物[核质](智人)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        同源DNA配对与链交换(智人)
        
        CX3复合物结合D-loop结构(智人)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3复合物[核质](智人)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        PALB2、BRCA2和RAD51介导的d -环形成(智人)
        
        3'悬空ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:BCDX2复合物[核质](智人)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        同源DNA配对和链交换的突触前阶段(智人)
        
        BCDX2复合物稳定RAD51丝(人类)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        3'悬空ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:BCDX2复合物[核质](智人)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        RAD51在切除的DNA dsb上结合BRCA2(现代人)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        d -环结构的解析(智人)
        
        通过Holliday结中间体解析d -环结构(人类)
        
        BLM介导双Holliday连接溶解(智人)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex[核质](智人)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        通过GEN1或SLX1A切割Holliday连接:SLX4:MUS81:EME1，(MUS81:EME2)(智人)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex[核质](智人)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex[核质](智人)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        修复合成后DNA的连接和Holliday结构的形成(智人)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3复合物[核质](智人)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex[核质](智人)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        MUS81:EME1,EME2分裂d环(智人)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3复合物[核质](智人)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3复合物[核质](智人)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        MUS81:EME1或MUS81:EME2切割d环的分辨率(智人)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3复合物[核质](智人)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        由GEN1或SLX1A切割的Holliday连接的分解:SLX4:MUS81:EME1，(MUS81:EME2)(智人)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex[核质](智人)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        通过合成相关链退火(SDSA)解析d -环结构(人类)
        
        d -环解离和链退火(人类)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3复合物[核质](智人)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合物:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
      - HDR单链退火(SSA)(人类)
        
        RAD51与RAD52的关联:DNA双链断裂端(智人)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        RAD52与RPA复合物在切除DNA dsb上的关联(智人)
        
        ATR:ATRIP:p-RPA:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        ERCC1:XPF切割SSA产生的皮瓣(智人)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA悬架和移位瓣:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](人类)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA dsb与annealed 3' ssDNA悬架和移位瓣:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](人类)
        
        ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA悬架和移位瓣:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:p-RPA:DNA dsb与annealed 3' ssDNA悬垂和移位皮瓣:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        p-RPA:带有退火的3' ssDNA悬垂和移位瓣的DNA dsb:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        RAD52促进切除的DNA dsb的单链退火(智人)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA悬架和移位瓣:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](人类)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA dsb与annealed 3' ssDNA悬架和移位瓣:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](人类)
        
        ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA悬架和移位瓣:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:p-RPA:DNA dsb与annealed 3' ssDNA悬垂和移位皮瓣:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        p-RPA:带有退火的3' ssDNA悬垂和移位瓣的DNA dsb:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
      - DNA双链断裂末端的加工(人类)
        
        DNA dsb的ATR激活(智人)
        
        ATR:ATRIP:RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        ATR:ATRIP:RPA:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        ATR磷酸化RPA2(智人)
        
        ATR:ATRIP:RPA:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        CHEK1在切除DNA dsb处的激活(智人)
        
        ATR:ATRIP:p-RPA:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        RPA复合物在切除DNA dsb上与ssDNA的结合(智人)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        BRCA1结合磷酸化的RBBP8(智人)
        
        DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        切除DNA dsb上ATR:ATRIP与RPA的结合(智人)
        
        ATR:ATRIP:RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        CHEK1被招募到被切除的DNA DSBs(智人)中
        
        ATR:ATRIP:p-RPA:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1[核质](智人)
        
        ATR:ATRIP:p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        p-RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        EXO1或DNA2与BLM或WRN复合物结合最初切除的DNA dsb以及BRIP1募集(智人)
        
        3'短悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        3'短悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        3'短悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        双链断端初始切除(智人)
        
        3'短悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        用EXO1或DNA2远距离切除DNA dsb(智人)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        3'短悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        3'短悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        PIAS4 SUMOylates MDC1(智人)
        
        DNA DNA双边带:p-MRN: p-S1981 Ac-K3016-ATM: KAT5: K63PolyUb-K14, K16, p-S139-H2AFX, Me2K21-HIST1H4A-Nucleosome: SUMO2: K1840, p-5T-MDC1: p-S102-WHSC1: RNF8: Zn2 +: SUMO1: p-T4827-HERC2: UBE2N: UBE2V2: RNF168: PIAS4: p-S25 S1778-TP53BP1: 5、2 t-brca1-a复杂(核浆)(智人)
        
        p-5S,2T-BRCA1-A复合物[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-5S,2T-BRCA1-A复合物[核质](智人)
        
        p-5S,2T-BRCA1-A复合物[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        RNF4泛素化MDC1(智人)
        
        DNA DNA双边带:p-MRN: p-S1981 Ac-K3016-ATM: KAT5: K63PolyUb-K14, K16, p-S139-H2AFX, Me2K21-HIST1H4A-Nucleosome: SUMO2: K1840, p-5T-MDC1: p-S102-WHSC1: RNF8: Zn2 +: SUMO1: p-T4827-HERC2: UBE2N: UBE2V2: RNF168: PIAS4: p-S25 S1778-TP53BP1: 5、2 t-brca1-a复杂(核浆)(智人)
        
        p-5S,2T-BRCA1-A复合物[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
  - 非同源末端连接(NHEJ)(人类)
    - 在DNA dsb上，RIF1和PAX1IP结合TP53BP1(现代人)
      - DNA dbs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5: k63polyb - k14,K16,p-S139-H2AFX, me2k21 - hist1h4a核小体:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-5S,2T-BRCA1-A复合物[核质](智人)
        
        p-5S,2T-BRCA1-A复合物[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
      - p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)

疾病(智人)

- DNA修复疾病(人类)
  - DNA双链断裂修复疾病(人类)
    - PALB2功能缺失导致HDR通过同源重组(HRR)缺陷(智人)
      - PALB2缺失BRCA1结合功能导致HDR通过同源重组修复(HRR)缺陷(智人)
        
        由于BRCA1结合中PALB2的功能缺失，PALB2、BRCA2和RAD51介导的D-loop形成缺陷(智人)
        
        3'悬空ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:BCDX2复合物[核质](智人)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)
      - PALB2缺失BRCA2/RAD51/RAD51C结合功能导致HDR通过同源重组修复(HRR)缺陷(智人)
        
        由于PALB2与BRCA2/RAD51/RAD51C结合功能的丧失，PALB2、BRCA2和RAD51介导的d -环形成缺陷(智人)
        
        3'悬空ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C复合物:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:BCDX2复合物[核质](智人)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)

基因表达(转录)(智人)

- RNA聚合酶II转录(人类)
  - 属类转录途径(智人)
    - TP53的转录调控(智人)
      - TP53活性的调控(智人)
        
        通过磷酸化调控TP53活性(人类)
        
        ATR使TP53磷酸化(智人)
        
        ATR:ATRIP:RPA:3'悬悬ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1[核质](智人)
        
        ATR:ATRIP:RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        RPA:3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        3'悬垂ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1[核质](智人)
        
        BRCA1-C复合体[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-5S-BRCA1:p-2T-BARD1[核质](智人)
        
        p-T714,T734-BARD1[核质](智人)

外部参考信息

外部引用

UniProt: Q99728 BARD1

基因名字

BARD1

链

链:1 - 777

参考基因

BioGPS基因:580 BARD1

宇宙(基因):BARD1 BARD1

CTD基因:580 BARD1

dbSNP基因:580 BARD1

运用:ENSG00000138376 BARD1

HGNC: 952 BARD1

KEGG基因(智人):580 BARD1

君主:580 BARD1

NCBI基因:580 BARD1

人类:601593 BARD1

UCSC: Q99728 BARD1

参考文本

其他标识符

0005390647

11756612 _a_at

16907960

1801年_at

205345 _at

227545 _at

242655 _at

243156 _at

2598096

2598098

2598100

2598101

2598102

2598104

2598107

2598108

2598109

2598110

2598115

2598116

2598117

2598119

2598120

2598123

2598124

2598126

2598128

2598129

2598130

46907 _at

47114 _at

54200 _at

580

8058695

A_23_P67771

GE532417

GE59408

GE87967

去:0000151

去:0000729

去:0001894

去:0003674

去:0003723

去:0004842

去:0005515

去:0005575

去:0005622

去:0005634

去:0005654

去:0005737

去:0006259

去:0006260

去:0006281

去:0006302

去:0006303

去:0006397

去:0006464

去:0006810

去:0006913

去:0006950

去:0006974

去:0007049

去:0007050

去:0007165

去:0008150

去:0008219

去:0009056

去:0009058

去:0015031

去:0016567

去:0016579

去:0016607

去:0016740

去:0019899

去:0019900

去:0031436

去:0031441

去:0032991

去:0034641

去:0036464

去:0042325

去:0042592

去:0042803

去:0043065

去:0043066

去:0043167

去:0043226

去:0045732

去:0046826

去:0046872

去:0046982

去:0070531

去:0085020

去:1901796

HMNXSV003025068

Hs.38894.0.A1_3p_at

Hs.54613.0.A1_3p_at

Hs.86617.0.A1_3p_at

ILMN_1785340

ILMN_1872456

ILMN_2074258

PH_hs_0003005

PH_hs_0003556

TC02002745.hg

TC02004804.hg

U76638_at

g4557348_3p_at

参与

作为…的组成部分

这个分子的其他形式

BARD1 G623E(核浆)

BARD1 C71Y(核浆)

BARD1 C53W(核浆)

BARD1 G623W(核浆)

BARD1 W34R(核浆)

BARD1 H68Y(核浆)

K6PolyUb、p-T714 T734-BARD1(核浆)

K6PolyUb-BARD1(核浆)

BARD1(核浆)

BARD1 C83G(核浆)

BARD1 C50G(核浆)

BARD1 L44R(核浆)

修改后的残留物

的名字

O-phospho-L-threonine在714

协调

714

PsiMod名字

O-phospho-L-threonine (MOD: 00047)

PsiMod定义

一种能有效地将l -苏氨酸残基转化为o-磷酸- l -苏氨酸的蛋白质修饰。

的名字

O-phospho-L-threonine在734

协调

734

PsiMod名字

O-phospho-L-threonine (MOD: 00047)

PsiMod定义

一种能有效地将l -苏氨酸残基转化为o-磷酸- l -苏氨酸的蛋白质修饰。

交叉引用

RefSeq

NP_000456.2，NP_001269472.1

OpenTargets

ENSG00000138376

下丘脑-垂体-肾上腺轴的

ENSG00000138376-BARD1

GeneCards

Q99728

运用

ENST00000260947，ENSP00000260947，ENST00000617164，ENSP00000481988，ENSG00000138376，ENST00000620057，ENSP00000480470

箴

Q99728

灯塔,目标

Q99728

Orphanet

18430

PDB

1 jm7，2 r1z，3 c5r，3 fa2，《国家贸易评估报告》2

扶少团团员(27)

加入	#实体	实体	信心得分	证据(完整)
UniProt: P38398 BRCA1	27	SUMO1-K109-BRCA1(核浆)(r - hsa - 2997644) SUMO2, 3-BRCA1(核浆)(r - hsa - 2997624) BRCA1 C64R(核浆)(r - hsa - 9700907) BRCA1 C61G(核浆)(r - hsa - 9700890) BRCA1 C39Y(核浆)(r - hsa - 9700938) BRCA1 H41R(核浆)(r - hsa - 9700921) BRCA1 C24R(核浆)(r - hsa - 9663198) BRCA1 H41A(核浆)(r - hsa - 9700927) BRCA1 M18T(核浆)(r - hsa - 9700911) BRCA1 C47G(核浆)(r - hsa - 9700941) BRCA1 C64G(核浆)(r - hsa - 9700899) BRCA1 C44F(核浆)(r - hsa - 9700944) BRCA1 T37R(核浆)(r - hsa - 9700934) BRCA1 C27A(核浆)(r - hsa - 9700916) BRCA1 H41Q(核浆)(r - hsa - 9700923) BRCA1 Q12Tfs * 5(核浆)(r - hsa - 9700953) BRCA1 E23Afs * 18(核浆)(r - hsa - 9700959) BRCA1 C61Y(核浆)(r - hsa - 9700894) BRCA1 C24F(核浆)(r - hsa - 9663206) BRCA1 E23Rfs * 18(核浆)(r - hsa - 9700960) BRCA1 E23Vfs * 17(核浆)(r - hsa - 9700967) p-S988、S1387 S1423、S1524 S1547-BRCA1(核浆)(r - hsa - 5683800) K6PolyUb、p-S988 S1387、S1423 S1524, S1547-BRCA1(核浆)(r - hsa - 9707298) 乳腺癌易感基因1(核浆)(r - hsa - 50949) K6PolyUb-BRCA1(核浆)(r - hsa - 9701022) K6PolyUb、p-S1387 S1423、S1524 S1547-BRCA1(核浆)(r - hsa - 9707290) p-S1387、S1423 S1524, S1547-BRCA1(核浆)(r - hsa - 75234)	0.951	17
UniProt: O95751 LDOC1			0.781	7
UniProt: Q08379 GOLGA2	3.	内质网-高尔基中间室膜(r - hsa - 2167933) p-S37-GOLGA2(高尔基体膜)(r - hsa - 2172179) GOLGA2(高尔基体膜)(r - hsa - 6808764)	0.718	6
UniProt: P33240 CSTF2	1	CSTF2(核浆)(r - hsa - 72003)	0.702	8
ChEBI: 61151标准			0．65	9
UniProt: Q05048 CSTF1	1	CSTF1(核浆)(r - hsa - 72001)	0.581	4
UniProt: O95453 PARN	1	PARN(胞质)(r - hsa - 430009)	0.577	4
ChEBI: 16864 ADP-RIBOSE			0.558	2
UniProt: O75031 HSF2B			0.556	3.
UniProt: Q8NHQ1 CEP70	1	CEP70(胞质)(r - hsa - 380257)	0.556	3.
UniProt: Q5JR59-3 MTUS2			0.556	3.
UniProt: Q15276 RABEP1	1	RABEP1[早期核内体膜](r - hsa - 2029004)	0.556	3.
完整:EBI-16435328 CCSB ORF ID			0.556	3.
UniProt: Q8IZU0 FAM9B			0.556	3.
UniProt: Q6A162 KRT40	1	KRT40(胞质)(r - hsa - 6809605)	0.556	3.
UniProt: Q9BVG8-5 KIFC3			0.556	3.
UniProt: Q13422-7 IKZF1			0.556	3.
UniProt: Q8N720 ZNF655	1	ZNF655(核浆)(r - hsa - 2127575)	0.556	3.
UniProt: O00471 EXOC5	2	EXOC5(胞质)(r - hsa - 5623383) EXOC5(胞质)(r - hsa - 265045)	0.556	3.
UniProt: Q9Y2T1 AXIN2	4	RibC-AXIN2(胞质)(r - hsa - 3640842) AXIN2(胞质)(r - hsa - 3640821) Ub-RibC-AXIN2(胞质)(r - hsa - 3640859) ub-AXIN2(胞质)(r - hsa - 4641131)	0.556	3.
UniProt: Q13077 TRAF1	3.	TRAF1(1 - 163)(胞质)(r - hsa - 5634199) TRAF1(胞质)(r - hsa - 5634163) TRAF1(164 - 416)(胞质)(r - hsa - 5634204)	0.556	3.
UniProt: P38398-1 BRCA1			0.524	3.
UniProt: Q9P2H0 CE126			0.508	2
UniProt: O14776 TCRG1			0.508	2
UniProt: O95251 KAT7	1	KAT7(核浆)(r - hsa - 3321823)	0.508	2
UniProt: Q9Y2X7 GIT1	2	GIT1(胞质)(r - hsa - 430326) p-Y383-GIT1(胞质)(r - hsa - 3928463)	0.508	2
UniProt: Q12873 CHD3	2	SUMO1-K1971-CHD3(核浆)(r - hsa - 8956372) CHD3(核浆)(r - hsa - 4657012)	0.508	2

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