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VPS28 [endosome membrane]
Stable Identifier
R-HSA-184342
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Late endosomal microautophagy (Homo sapiens)
Substrate translocates into late endosomal lumen (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
HCMV Infection (Homo sapiens)
HCMV Late Events (Homo sapiens)
HCMV Final Envelopment (Homo sapiens)
ESCRT Regulator Complex [cytosol] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
HCMV Formation of Final Envelopment Complex (Homo sapiens)
ESCRT Regulator Complex [cytosol] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
HIV Infection (Homo sapiens)
艾滋病毒Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Assembly Of The HIV Virion (Homo sapiens)
Synthesis And Processing Of GAG, GAGPOL Polyproteins (Homo sapiens)
Membrane binding and targetting of GAG proteins (Homo sapiens)
Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
Transport of GAG to the Plasma Membrane (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
Budding and maturation of HIV virion (Homo sapiens)
HIV Virion Budding (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
Recruitment Of HIV Virion Budding Machinery (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Endosomal Sorting Complex Required For Transport (ESCRT) (Homo sapiens)
Cargo Recognition And Sorting (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
Cargo Sequestration (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS28 [endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UK41 VPS28
Gene Names
VPS28
Chain
chain:1-221
Reference Genes
BioGPS Gene:51160 VPS28
COSMIC (genes):VPS28 VPS28
CTD Gene:51160 VPS28
dbSNP基因:51160 VPS28
ENSEMBL:ENSG00000160948 VPS28
ENSEMBL:ENSG00000285339 VPS28
HGNC:18178 VPS28
KEGG Gene (Homo sapiens):51160 VPS28
Monarch:51160 VPS28
NCBI Gene:51160 VPS28
OMIM:611952 VPS28
UCSC:Q9UK41 VPS28
Reference Transcript
RefSeq:NM_016208.3 VPS28
RefSeq:NM_183057.2 VPS28
Other Identifiers
0001050452
0006900068
11716209_a_at
11756567_x_at
17082676
218679_s_at
3158610
3158611
3158612
3158613
3158614
3158615
3158617
3158619
3158621
3158622
3158624
3158628
3158630
3158634
3158635
3158637
51160
78782_at
8153776
A_23_P31903
GE58701
GO:0000813
GO:0003674
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005768
GO:0005769
GO:0005829
GO:0005886
GO:0006464
GO:0006810
GO:0006914
GO:0007034
GO:0008150
GO:0009056
GO:0010008
GO:0015031
GO:0016020
GO:0016192
GO:0016197
GO:0016236
GO:0019058
GO:0022607
GO:0031397
去:0031410
GO:0031902
GO:0032182
去:0032509
GO:0032991
GO:0036258
GO:0039702
GO:0043130
GO:0043162
GO:0043226
GO:0043328
GO:0043657
GO:0044403
GO:0044877
GO:0045732
GO:0070062
GO:0075733
GO:2000397
HMNXSV003020937
ILMN_1790797
ILMN_2339863
PH_hs_0028382
TC08001750.hg
g7705884_3p_s_at
Participates
as a component of
ESCRT-I [endosome membrane] (Homo sapiens)
Inferred To
Ghost homologue of VPS28 [endosome membrane]
(Bos taurus)
Ghost homologue of VPS28 [endosome membrane]
(Gallus gallus)
vps-28 [endosome membrane]
(Caenorhabditis elegans)
Vps28 [endosome membrane]
(Drosophila melanogaster)
Vps28 [endosome membrane]
(Mus musculus)
Vps28 [endosome membrane]
(鼠形)
vps28 [endosome membrane]
(Danio rerio)
vps28 [endosome membrane]
(Dictyostelium discoideum)
vps28 [endosome membrane]
(Xenopus tropicalis)
VPS28 [endosome membrane]
(Canis familiaris)
VPS28 [endosome membrane]
(Saccharomyces cerevisiae)
VPS28 [endosome membrane]
(Sus scrofa)
Cross References
RefSeq
NP_898880.1
,
NP_057292.1
OpenTargets
ENSG00000160948
GeneCards
Q9UK41
HPA
ENSG00000160948-VPS28
Ensembl
ENSP00000434064
,
ENST00000643186
,
ENST00000646588
,
ENSP00000496519
,
ENSP00000495408
,
ENST00000642202
,
ENST00000529182
,
ENSP00000434556
,
ENSG00000160948
,
ENST00000642867
,
ENST00000526054
,
ENST00000377348
,
ENSP00000366565
,
ENSG00000285339
,
ENSP00000496693
,
ENST00000292510
,
ENSP00000494521
,
ENSP00000292510
PRO
Q9UK41
Pharos - Targets
Q9UK41
PDB
6VME
扶少团团员(3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.666
16
UniProt:P14373 TRIM27
2
TRIM27 [cytosol]
(R-HSA-8851002)
TRIM27 [nucleoplasm]
(R-HSA-2997690)
0.556
3
UniProt:Q08379 GOLGA2
3
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
6
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