Reactome | Homologues of SP1 [nucleoplasm]

Homologues of SP1 [nucleoplasm]

Stable Identifier

R-DME-1592223-3

Type

Set [DefinedSet]

Species

Drosophila melanogaster

Compartment

nucleoplasm

地点在PathwayBrowser

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Gene expression (Transcription) (Drosophila melanogaster)

- RNA Polymerase II Transcription (Drosophila melanogaster)
  - Generic Transcription Pathway (Drosophila melanogaster)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Drosophila melanogaster)
      - SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Drosophila melanogaster)
        
        SMAD2/3:SMAD4 heterotrimer binds SP1 (Drosophila melanogaster)
        
        Homologues of SP1 [nucleoplasm] (Drosophila melanogaster)
        
        p-2S-SMAD2/3:SMAD4:SP1 [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SP1 [nucleoplasm] (Drosophila melanogaster)
  - RNA polymerase II transcribes snRNA genes (Drosophila melanogaster)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SP1 [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SP1 [nucleoplasm] (Drosophila melanogaster)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SP1 [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SP1 [nucleoplasm] (Drosophila melanogaster)
    - Integrator complex processes the 3' end of snRNA (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SP1 [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SP1 [nucleoplasm] (Drosophila melanogaster)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SP1 [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SP1 [nucleoplasm] (Drosophila melanogaster)
    - RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Drosophila melanogaster)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SP1 [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of SP1 [nucleoplasm] (Drosophila melanogaster)

参与者

members

Participates

as an input of

as a component of

Inferred From

SP1 [nucleoplasm](Homo sapiens)

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