BioPAX pathway converted from "Keratinization" in the Reactome database. Keratinization This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp Formation of the cornified envelope This event has been computationally inferred from an event that has been demonstrated in another species.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp LEFT-TO-RIGHT 3.1.1.34 LIPs hydrolyse TG to DAG and RCOOH This event has been computationally inferred from an event that has been demonstrated in another species.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp TAGs triacylglycerols triglyceride Reactome DB_ID: 171126 extracellular region GENE ONTOLOGY GO:0005576 triglyceride [ChEBI:17855] triglyceride ChEBI CHEBI:17855 Reactome Database ID Release 77 171126 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=171126 Reactome R-ALL-171126 3 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-171126.3 Reactome //www.joaskin.com H2O water Reactome DB_ID: 109276 water [ChEBI:15377] water ChEBI CHEBI:15377 Reactome Database ID Release 77 109276 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=109276 Reactome r - - 109276 4 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-109276.4 COMPOUND C00001 additional information MI MI:0361 RCOOH carboxylate carboxylic acid Reactome DB_ID: 6789319 carboxylic acid [ChEBI:33575] carboxylic acid RC(=O)OH acidos carboxilicos Karbonsaeure Carbonsaeuren acides carboxyliques Carbonsaeure acide carboxylique acido carboxilico ChEBI CHEBI:33575 Reactome Database ID Release 77 6789319 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=6789319 Reactome R-ALL-6789319 3 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-6789319.3 DAG DAGs diacylglycerols diglyceride diglycerides Reactome DB_ID: 174675 diglyceride [ChEBI:18035] diglyceride ChEBI CHEBI:18035 Reactome Database ID Release 77 174675 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=174675 Reactome R-ALL-174675 4 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-174675.4 ACTIVATION Converted from EntitySet in Reactome lipases keratinocyte LIPs LIPG,J,K,M,N Reactome DB_ID: 10551749 Converted from EntitySet in Reactome Homologues of LIPK Reactome DB_ID: 10551603 LIPK Dmel\CG17097 E2QCS7 Reactome DB_ID: 10551491 UniProt:E2QCS7 Dmel\CG17097 黑腹果蝇 NCBI Taxonomy 7227 UniProt E2QCS7 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551491 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551491 Reactome R-DME-6789300 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300.1 Lip4 LIPK M9PCU5 Reactome DB_ID: 10551496 UniProt:M9PCU5 Lip4 UniProt M9PCU5 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551496 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551496 Reactome R-DME-6789300-2 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-2.1 Lip1 LIPK O46107 Reactome DB_ID: 10551501 UniProt:O46107 Lip1 UniProt O46107 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551501 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551501 Reactome R-DME-6789300-3 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-3.1 Lip3 LIPK O46108 Reactome DB_ID: 10551506 UniProt:O46108 Lip3 UniProt O46108 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551506 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551506 Reactome R-DME-6789300-4 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-4.1 LIPK Dmel\CG11598 Q0KI77 Reactome DB_ID: 10551511 UniProt:Q0KI77 Dmel\CG11598 UniProt Q0KI77 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551511 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551511 Reactome R-DME-6789300-5 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-5.1 LIPK Dmel\CG8093 Q4V6L4 Reactome DB_ID: 10551516 UniProt:Q4V6L4 Dmel\CG8093 UniProt Q4V6L4 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551516 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551516 Reactome R-DME-6789300-6 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-6.1 LIPK Dmel\CG11406 Q59E63 Reactome DB_ID: 10551521 UniProt:Q59E63 Dmel\CG11406 UniProt Q59E63 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551521 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551521 Reactome R-DME-6789300-7 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-7.1 LIPK CG5990 Q8IMS3 Reactome DB_ID: 10551526 UniProt:Q8IMS3 CG5990 UniProt Q8IMS3 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551526 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551526 Reactome R-DME-6789300-8 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-8.1 LIPK Dmel\CG3635 Q9V9N3 Reactome DB_ID: 10551531 UniProt:Q9V9N3 Dmel\CG3635 UniProt Q9V9N3 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551531 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551531 Reactome R-DME-6789300-9 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-9.1 LIPK CG5990 Q9VBK6 Reactome DB_ID: 10551536 UniProt:Q9VBK6 CG5990 UniProt Q9VBK6 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551536 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551536 Reactome R-DME-6789300-10 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-10.1 LIPK Dmel\CG6753 Q9VG46 Reactome DB_ID: 10551541 UniProt:Q9VG46 Dmel\CG6753 UniProt Q9VG46 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551541 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551541 Reactome R-DME-6789300-11 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-11.1 LIPK Dmel\CG11608 Q9VG47 Reactome DB_ID: 10551546 UniProt:Q9VG47 Dmel\CG11608 UniProt Q9VG47 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551546 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551546 Reactome R-DME-6789300-12 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-12.1 LIPK Dmel\CG11600 Q9VG48 Reactome DB_ID: 10551551 UniProt:Q9VG48 Dmel\CG11600 UniProt Q9VG48 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551551 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551551 Reactome R-DME-6789300-13 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-13.1 LIPK CG12294 Q9VG50 Reactome DB_ID: 10551556 UniProt:Q9VG50 CG12294 UniProt Q9VG50 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551556 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551556 Reactome R-DME-6789300-14 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-14.1 Lip2 LIPK Q9VKR5 Reactome DB_ID: 10551561 UniProt:Q9VKR5 Lip2 UniProt Q9VKR5 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551561 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551561 Reactome R-DME-6789300-15 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-15.1 LIPK CG17099 Q9VKS5 Reactome DB_ID: 10551566 UniProt:Q9VKS5 CG17099 UniProt Q9VKS5 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551566 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551566 Reactome R-DME-6789300-16 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-16.1 Acp LIPK Q9VKS9 Reactome DB_ID: 10551571 UniProt:Q9VKS9 Acp UniProt Q9VKS9 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551571 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551571 Reactome R-DME-6789300-17 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-17.1 LIPK CG17093 Q9VKT1 Reactome DB_ID: 10551576 UniProt:Q9VKT1 CG17093 UniProt Q9VKT1 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551576 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551576 Reactome R-DME-6789300-18 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-18.1 LIPK Dmel\CG7329 Q9VKT2 Reactome DB_ID: 10551581 UniProt:Q9VKT2 Dmel\CG7329 UniProt Q9VKT2 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551581 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551581 Reactome R-DME-6789300-19 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-19.1 LIPK Dmel\CG18302 Q9VKT7 Reactome DB_ID: 10551586 UniProt:Q9VKT7 Dmel\CG18302 UniProt Q9VKT7 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551586 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551586 Reactome R-DME-6789300-20 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-20.1 LIPK Dmel\CG18301 Q9VKT8 Reactome DB_ID: 10551591 UniProt:Q9VKT8 Dmel\CG18301 UniProt Q9VKT8 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551591 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551591 Reactome R-DME-6789300-21 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-21.1 mag LIPK Q9VPE9 Reactome DB_ID: 10551596 UniProt:Q9VPE9 mag UniProt Q9VPE9 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551596 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551596 Reactome R-DME-6789300-22 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-22.1 LIPK Dmel\CG2772 Q9VQQ5 Reactome DB_ID: 10551601 UniProt:Q9VQQ5 Dmel\CG2772 UniProt Q9VQQ5 20 EQUAL 399 EQUAL Reactome Database ID Release 77 10551601 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551601 Reactome R-DME-6789300-23 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-23.1 Reactome Database ID Release 77 10551603 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551603 Reactome R-DME-6789300-24 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789300-24.1 Converted from EntitySet in Reactome Homologues of LIPM Reactome DB_ID: 10551651 LIPM Dmel\CG17097 E2QCS7 Reactome DB_ID: 10551605 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551605 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551605 Reactome R-DME-6789306 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306.1 Lip4 LIPM M9PCU5 Reactome DB_ID: 10551607 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551607 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551607 Reactome R-DME-6789306-2 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-2.1 Lip1 LIPM O46107 Reactome DB_ID: 10551609 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551609 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551609 Reactome R-DME-6789306-3 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-3.1 Lip3 LIPM O46108 Reactome DB_ID: 10551611 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551611 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551611 Reactome R-DME-6789306-4 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-4.1 LIPM Dmel\CG11598 Q0KI77 Reactome DB_ID: 10551613 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551613 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551613 Reactome R-DME-6789306-5 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-5.1 LIPM Dmel\CG8093 Q4V6L4 Reactome DB_ID: 10551615 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551615 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551615 Reactome R-DME-6789306-6 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-6.1 LIPM Dmel\CG11406 Q59E63 Reactome DB_ID: 10551617 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551617 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551617 Reactome R-DME-6789306-7 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-7.1 LIPM CG5990 Q8IMS3 Reactome DB_ID: 10551619 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551619 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551619 Reactome R-DME-6789306-8 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-8.1 LIPM Dmel\CG3635 Q9V9N3 Reactome DB_ID: 10551621 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551621 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551621 Reactome R-DME-6789306-9 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-9.1 LIPM CG5990 Q9VBK6 Reactome DB_ID: 10551623 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551623 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551623 Reactome R-DME-6789306-10 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-10.1 LIPM Dmel\CG6753 Q9VG46 Reactome DB_ID: 10551625 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551625 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551625 Reactome R-DME-6789306-11 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-11.1 LIPM Dmel\CG11608 Q9VG47 Reactome DB_ID: 10551627 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551627 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551627 Reactome R-DME-6789306-12 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-12.1 LIPM Dmel\CG11600 Q9VG48 Reactome DB_ID: 10551629 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551629 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551629 Reactome R-DME-6789306-13 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-13.1 LIPM CG12294 Q9VG50 Reactome DB_ID: 10551631 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551631 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551631 Reactome R-DME-6789306-14 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-14.1 Lip2 LIPM Q9VKR5 Reactome DB_ID: 10551633 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551633 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551633 Reactome R-DME-6789306-15 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-15.1 LIPM CG17099 Q9VKS5 Reactome DB_ID: 10551635 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551635 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551635 Reactome R-DME-6789306-16 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-16.1 Acp LIPM Q9VKS9 Reactome DB_ID: 10551637 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551637 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551637 Reactome R-DME-6789306-17 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-17.1 LIPM CG17093 Q9VKT1 Reactome DB_ID: 10551639 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551639 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551639 Reactome R-DME-6789306-18 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-18.1 LIPM Dmel\CG7329 Q9VKT2 Reactome DB_ID: 10551641 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551641 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551641 Reactome R-DME-6789306-19 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-19.1 LIPM Dmel\CG18302 Q9VKT7 Reactome DB_ID: 10551643 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551643 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551643 Reactome R-DME-6789306-20 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-20.1 LIPM Dmel\CG18301 Q9VKT8 Reactome DB_ID: 10551645 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551645 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551645 Reactome R-DME-6789306-21 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-21.1 mag LIPM Q9VPE9 Reactome DB_ID: 10551647 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551647 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551647 Reactome R-DME-6789306-22 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-22.1 LIPM Dmel\CG2772 Q9VQQ5 Reactome DB_ID: 10551649 34 EQUAL 423 EQUAL Reactome Database ID Release 77 10551649 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551649 Reactome R-DME-6789306-23 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-23.1 Reactome Database ID Release 77 10551651 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551651 Reactome R-DME-6789306-24 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789306-24.1 Converted from EntitySet in Reactome Homologues of LIPN Reactome DB_ID: 10551699 LIPN Dmel\CG17097 E2QCS7 Reactome DB_ID: 10551653 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551653 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551653 Reactome R-DME-6789321 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321.1 Lip4 LIPN M9PCU5 Reactome DB_ID: 10551655 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551655 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551655 Reactome R-DME-6789321-2 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-2.1 Lip1 LIPN O46107 Reactome DB_ID: 10551657 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551657 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551657 Reactome R-DME-6789321-3 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-3.1 Lip3 LIPN O46108 Reactome DB_ID: 10551659 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551659 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551659 Reactome R-DME-6789321-4 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-4.1 LIPN Dmel\CG11598 Q0KI77 Reactome DB_ID: 10551661 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551661 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551661 Reactome R-DME-6789321-5 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-5.1 LIPN Dmel\CG8093 Q4V6L4 Reactome DB_ID: 10551663 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551663 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551663 Reactome R-DME-6789321-6 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-6.1 LIPN Dmel\CG11406 Q59E63 Reactome DB_ID: 10551665 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551665 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551665 Reactome R-DME-6789321-7 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-7.1 LIPN CG5990 Q8IMS3 Reactome DB_ID: 10551667 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551667 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551667 Reactome R-DME-6789321-8 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-8.1 LIPN Dmel\CG3635 Q9V9N3 Reactome DB_ID: 10551669 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551669 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551669 Reactome R-DME-6789321-9 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-9.1 LIPN CG5990 Q9VBK6 Reactome DB_ID: 10551671 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551671 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551671 Reactome R-DME-6789321-10 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-10.1 LIPN Dmel\CG6753 Q9VG46 Reactome DB_ID: 10551673 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551673 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551673 Reactome R-DME-6789321-11 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-11.1 LIPN Dmel\CG11608 Q9VG47 Reactome DB_ID: 10551675 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551675 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551675 Reactome R-DME-6789321-12 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-12.1 LIPN Dmel\CG11600 Q9VG48 Reactome DB_ID: 10551677 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551677 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551677 Reactome R-DME-6789321-13 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-13.1 LIPN CG12294 Q9VG50 Reactome DB_ID: 10551679 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551679 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551679 Reactome R-DME-6789321-14 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-14.1 Lip2 LIPN Q9VKR5 Reactome DB_ID: 10551681 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551681 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551681 Reactome R-DME-6789321-15 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-15.1 LIPN CG17099 Q9VKS5 Reactome DB_ID: 10551683 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551683 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551683 Reactome R-DME-6789321-16 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-16.1 Acp LIPN Q9VKS9 Reactome DB_ID: 10551685 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551685 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551685 Reactome R-DME-6789321-17 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-17.1 LIPN CG17093 Q9VKT1 Reactome DB_ID: 10551687 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551687 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551687 Reactome R-DME-6789321-18 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-18.1 LIPN Dmel\CG7329 Q9VKT2 Reactome DB_ID: 10551689 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551689 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551689 Reactome R-DME-6789321-19 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-19.1 LIPN Dmel\CG18302 Q9VKT7 Reactome DB_ID: 10551691 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551691 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551691 Reactome R-DME-6789321-20 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-20.1 LIPN Dmel\CG18301 Q9VKT8 Reactome DB_ID: 10551693 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551693 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551693 Reactome R-DME-6789321-21 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-21.1 mag LIPN Q9VPE9 Reactome DB_ID: 10551695 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551695 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551695 Reactome R-DME-6789321-22 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-22.1 LIPN Dmel\CG2772 Q9VQQ5 Reactome DB_ID: 10551697 19 EQUAL 398 EQUAL Reactome Database ID Release 77 10551697 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551697 Reactome R-DME-6789321-23 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-23.1 Reactome Database ID Release 77 10551699 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551699 Reactome R-DME-6789321-24 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789321-24.1 Converted from EntitySet in Reactome Homologues of LIPJ Reactome DB_ID: 10551747 LIPJ Dmel\CG17097 E2QCS7 Reactome DB_ID: 10551701 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551701 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551701 Reactome R-DME-6789309 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309.1 Lip4 LIPJ M9PCU5 Reactome DB_ID: 10551703 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551703 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551703 Reactome R-DME-6789309-2 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-2.1 Lip1 LIPJ O46107 Reactome DB_ID: 10551705 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551705 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551705 Reactome R-DME-6789309-3 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-3.1 Lip3 LIPJ O46108 Reactome DB_ID: 10551707 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551707 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551707 Reactome R-DME-6789309-4 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-4.1 LIPJ Dmel\CG11598 Q0KI77 Reactome DB_ID: 10551709 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551709 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551709 Reactome R-DME-6789309-5 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-5.1 LIPJ Dmel\CG8093 Q4V6L4 Reactome DB_ID: 10551711 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551711 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551711 Reactome R-DME-6789309-6 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-6.1 LIPJ Dmel\CG11406 Q59E63 Reactome DB_ID: 10551713 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551713 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551713 Reactome R-DME-6789309-7 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-7.1 LIPJ CG5990 Q8IMS3 Reactome DB_ID: 10551715 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551715 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551715 Reactome R-DME-6789309-8 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-8.1 LIPJ Dmel\CG3635 Q9V9N3 Reactome DB_ID: 10551717 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551717 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551717 Reactome R-DME-6789309-9 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-9.1 LIPJ CG5990 Q9VBK6 Reactome DB_ID: 10551719 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551719 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551719 Reactome R-DME-6789309-10 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-10.1 LIPJ Dmel\CG6753 Q9VG46 Reactome DB_ID: 10551721 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551721 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551721 Reactome R-DME-6789309-11 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-11.1 LIPJ Dmel\CG11608 Q9VG47 Reactome DB_ID: 10551723 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551723 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551723 Reactome R-DME-6789309-12 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-12.1 LIPJ Dmel\CG11600 Q9VG48 Reactome DB_ID: 10551725 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551725 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551725 Reactome R-DME-6789309-13 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-13.1 LIPJ CG12294 Q9VG50 Reactome DB_ID: 10551727 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551727 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551727 Reactome R-DME-6789309-14 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-14.1 Lip2 LIPJ Q9VKR5 Reactome DB_ID: 10551729 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551729 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551729 Reactome R-DME-6789309-15 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-15.1 LIPJ CG17099 Q9VKS5 Reactome DB_ID: 10551731 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551731 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551731 Reactome R-DME-6789309-16 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-16.1 Acp LIPJ Q9VKS9 Reactome DB_ID: 10551733 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551733 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551733 Reactome R-DME-6789309-17 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-17.1 LIPJ CG17093 Q9VKT1 Reactome DB_ID: 10551735 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551735 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551735 Reactome R-DME-6789309-18 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-18.1 LIPJ Dmel\CG7329 Q9VKT2 Reactome DB_ID: 10551737 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551737 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551737 Reactome R-DME-6789309-19 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-19.1 LIPJ Dmel\CG18302 Q9VKT7 Reactome DB_ID: 10551739 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551739 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551739 Reactome R-DME-6789309-20 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-20.1 LIPJ Dmel\CG18301 Q9VKT8 Reactome DB_ID: 10551741 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551741 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551741 Reactome R-DME-6789309-21 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-21.1 mag LIPJ Q9VPE9 Reactome DB_ID: 10551743 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551743 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551743 Reactome R-DME-6789309-22 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-22.1 LIPJ Dmel\CG2772 Q9VQQ5 Reactome DB_ID: 10551745 1 EQUAL 366 EQUAL Reactome Database ID Release 77 10551745 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551745 Reactome R-DME-6789309-23 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-23.1 Reactome Database ID Release 77 10551747 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551747 Reactome R-DME-6789309-24 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789309-24.1 Reactome Database ID Release 77 10551749 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551749 Reactome R-DME-6789317 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789317.1 GENE ONTOLOGY GO:0004465 gene ontology term for cellular function MI MI:0355 Same Catalyst Activity Reactome Database ID Release 77 10551750 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551750 Reactome Database ID Release 77 10551752 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10551752 Reactome R-DME-6789310 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6789310.1 Lipases are enzymes that hydrolyse dietary lipids such as fats, oils and triglycerides. The majority of human lipases are secreted by the pancreas and function mainly in the digestive system. Lipase members K, M and N (LIPK, M and N), however, all appear to play a role in the last step of keratinocyte differentiation where they are proposed to hydrolyse triglycerides to free fatty acids and glycerol which is essential to stratum corneum hydration (Toulza et al. 2007). 17562024 Pubmed 2007 Large-scale identification of human genes implicated in epidermal barrier function Toulza, Eve Mattiuzzo, Nicolas R Galliano, Marie-Florence Jonca, Nathalie Dossat, Carole Jacob, Daniel de Daruvar, Antoine Wincker, Patrick Serre, Guy Guerrin, Marina Genome Biol. 8:R107 inferred from electronic annotation EVIDENCE CODE ECO:0000203 Reactome Database ID Release 77 10571559 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10571559 Reactome R-DME-6809371 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6809371.1 GENE ONTOLOGY GO:0070268 gene ontology term for cellular process MI MI:0359 As keratinocytes progress towards the upper epidermis, they undergo a unique process of cell death termed cornification (Eckhart et al. 2013). This involves the crosslinking of keratinocyte proteins such as loricrin and involucrin by transglutaminases and the breakdown of the nucleus and other organelles by intracellular and secreted proteases (Eckhart et al. 2000, Denecker et al. 2008). This process is strictly regulated by the Ca2+ concentration gradient in the epidermis (Esholtz et al. 2014). Loricrin and involucrin are encoded in ‘Epidermal Differentiation Complex’ linked to a large number of genes encoding nonredundant components of the CE (Kypriotou et al. 2012, Niehues et al. 2016). Keratinocytes produce specialized proteins and lipids which are used to construct the cornified envelope (CE), a heavily crosslinked submembranous layer that confers rigidity to the upper epidermis, allows keratin filaments to attach to any location in the cell membrane (Kirfel et al. 2003) and acts as a water-impermeable barrier. The CE has two functional parts: covalently cross-linked proteins (10 nm thick) that comprise the backbone of the envelope and covalently linked lipids (5 nm thick) that coat the exterior (Eckert et al. 2005). Desmosomal components are crosslinked to the CE to form corneodesmosomes, which bind cornified cells together (Ishida-Yamamoto et al. 2011). Mature terminally differentiated cornified cells consist mostly of keratin filaments covalently attached to the CE embedded in lipid lamellae (Kalinin et al. 2002). The exact composition of the cornified envelope varies between epithelia (Steinert et al. 1998); the relative amino-acid composition of the proteins used may determine differential mechanical properties (Kartasova et al. 1996). 11121154 Pubmed 2000 Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation Eckhart, L Declercq, W Ban, J Rendl, M Lengauer, B Mayer, C Lippens, S Vandenabeele, P Tschachler, E J. Invest. Dermatol. 115:1148-51 15737187 Pubmed 2005 Transglutaminase function in epidermis Eckert, Richard L Sturniolo, Michael T Broome, Ann-Marie Ruse, Monica Rorke, Ellen A J. Invest. Dermatol. 124:481-92 26556599 Pubmed 2016 Late cornified envelope (LCE) proteins: distinct expression patterns of LCE2 and LCE3 members suggest nonredundant roles in human epidermis and other epithelia Niehues, H van Vlijmen-Willems, I M J J Bergboer, J G M Kersten, F F J Narita, M Hendriks, W J A J van den Bogaard, E H Zeeuwen, P L J M Schalkwijk, J Br. J. Dermatol. 174:795-802 8601731 Pubmed 1996 Sequence and expression patterns of mouse SPR1: Correlation of expression with epithelial function Kartasova, T Darwiche, N Kohno, Y Koizumi, H Osada, S Huh, N Lichti, U Steinert, P M Kuroki, T J. Invest. Dermatol. 106:294-304 22507538 Pubmed 2012 The human epidermal differentiation complex: cornified envelope precursors, S100 proteins and the 'fused genes' family Kypriotou, Magdalini Huber, Marcel Hohl, D Exp. Dermatol. 21:643-9 15803139 Pubmed 2005 The cornified envelope: a model of cell death in the skin Candi, Eleonora Schmidt, Rainer Melino, Gerry Nat. Rev. Mol. Cell Biol. 6:328-40 12613658 Pubmed 2003 Keratins: a structural scaffold with emerging functions Kirfel, J Magin, T M Reichelt, J Cell. Mol. Life Sci. 60:56-71 9565599 Pubmed 1998 Biochemical evidence that small proline-rich proteins and trichohyalin function in epithelia by modulation of the biomechanical properties of their cornified cell envelopes Steinert, P M Kartasova, T Marekov, L N J. Biol. Chem. 273:11758-69 23792051 Pubmed 2013 Cell death by cornification Eckhart, Leopold Lippens, Saskia Tschachler, Erwin Declercq, Wim Biochim. Biophys. Acta 1833:3471-80 21545505 Pubmed 2011 Order and disorder in corneocyte adhesion Ishida-Yamamoto, Akemi Igawa, Satomi Kishibe, Mari J. Dermatol. 38:645-54 25514792 Pubmed 2014 Calcium--a central regulator of keratinocyte differentiation in health and disease Elsholz, Floriana Harteneck, Christian Muller, Walter Friedland, Kristina Eur J Dermatol 24:650-61 18250198 Pubmed 2008 Caspase-14 reveals its secrets Denecker, Geertrui Ovaere, Petra Vandenabeele, P Declercq, Wim J. Cell Biol. 180:451-8 Reactome Database ID Release 77 10571561 数据库标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10571561 Reactome R-DME-6805567 1 Reactome稳定的标识符。使用这个URL连接到the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-DME-6805567.1 GENE ONTOLOGY GO:0031424 Keratins are the major structural protein of vertebrate epidermis, constituting up to 85% of a fully differentiated keratinocyte (Fuchs 1995). Keratins belong to a superfamily of intermediate filament (IF) proteins that form alpha-helical coiled-coil dimers, which associate laterally and end-to-end to form approximately 10 nm diameter filaments. Keratin filaments are heteropolymeric, formed from equal amounts of acidic type I and basic /neutral type 2 keratins. Humans have 54 keratin genes (Schweitzer et al. 2006). They have highly specific expression patterns, related to the epithelial type and stage of differentiation. Roughly half of human keratins are specific to hair follicles (Langbein & Schweizer 2005). Keratin filaments bundle into tonofilaments that span the cytoplasm and bind to desmosomes and other cell membrane structures (Waschke 2008). This reflects their primary function, maintaining the mechanical stability of individual cells and epithelial tissues (Moll et al. 2008). 18461349 Pubmed 2008 The human keratins: biology and pathology Moll, Roland Divo, Markus Langbein, Lutz Histochem. Cell Biol. 129:705-33 15797458 Pubmed 2005 Keratins of the human hair follicle Langbein, Lutz Schweizer, Jürgen Int. Rev. Cytol. 243:1-78 18386043 Pubmed 2008 The desmosome and pemphigus Waschke, Jens Histochem. Cell Biol. 130:21-54 16831889 Pubmed 2006 New consensus nomenclature for mammalian keratins Schweizer, Jürgen Bowden, Paul E Coulombe, Pierre A Langbein, Lutz Lane, E Birgitte Magin, Thomas M Maltais, Lois Omary, M Bishr Parry, David A D Rogers, Michael A Wright, Mathew W J. Cell Biol. 174:169-74 8689554 Pubmed 1995 Keratins and the skin Fuchs, E Annu. Rev. Cell Dev. Biol. 11:123-53