BioPAX pathway converted from "citrate <=> isocitrate" in the Reactome database. LEFT-TO-RIGHT 4.2.1.3 citrate <=> isocitrate This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp CIT Citrate citric acid 2-Hydroxy-1,2,3-propanetricarboxylic acid 2-Hydroxytricarballylic acid Reactome DB_ID: 29654 mitochondrial matrix GENE ONTOLOGY GO:0005759 citric acid [ChEBI:30769] citric acid ChEBI CHEBI:30769 Reactome Database ID Release 77 29654 数据库标识符。使用这个URL connect to the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=29654 Reactome R-ALL-29654 3 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-29654.3 Reactome //www.joaskin.com COMPOUND C00158 additional information MI 小姐:0361 ISCIT Isocitrate D-threo-isocitric acid (1R,2S)-1-Hydroxypropane-1,2,3-tricarboxylate Isocitric acid 1-Hydroxytricarballylic acid 1-Hydroxypropane-1,2,3-tricarboxylic acid D-erythro-Isocitric acid Reactome DB_ID: 29938 D-threo-isocitric acid [ChEBI:151] D-threo-isocitric acid ChEBI CHEBI:151 Reactome Database ID Release 77 29938 数据库标识符。使用这个URL connect to the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=29938 Reactome R-ALL-29938 3 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-ALL-29938.3 COMPOUND C00451 COMPOUND C00311 ACTIVATION ACO2 ACO2 Q5ZMW1 Reactome DB_ID: 10412189 UniProt:Q5ZMW1 ACO2 Gallus gallus NCBI Taxonomy 9031 UniProt Q5ZMW1 28 EQUAL 780 EQUAL Reactome Database ID Release 77 10412189 数据库标识符。使用这个URL connect to the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10412189 Reactome R-GGA-70968 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-GGA-70968.1 GENE ONTOLOGY GO:0003994 gene ontology term for cellular function MI MI:0355 Same Catalyst Activity Reactome Database ID Release 77 10412190 数据库标识符。使用这个URL connect to the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10412190 Reactome Database ID Release 77 10412192 数据库标识符。使用这个URL connect to the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser?DB=gk_current&ID=10412192 Reactome R-GGA-70971 1 Reactome stable identifier. Use this URL to connect to the web page of this instance in Reactome: //www.joaskin.com/cgi-bin/eventbrowser_st_id?ST_ID=R-GGA-70971.1 Mitochondrial aconitase reversibly converts citrate to isocitrate via a cis-aconitate intermediate. Mitochondrial aconitase activity has been demonstrated in diverse human tissue extracts (Slaughter et al. 1975) and a protein homologous to the well-characterized porcine enzyme has been purified from human tissues (Baldwin et al. 1991). 1052766 Pubmed 1975 Aconitase polymorphism in man Slaughter, CA Hopkinson, DA Harris, H Ann Hum Genet 39:193-202 1946331 Pubmed 1991 Purification and partial amino acid sequence of human aconitase Baldwin, GS Seet, KL Callaghan, J Toncich, G Toh, BH Moritz, RL Rubira, MR Simpson, R Protein Seq Data Anal 4:63-67 inferred from electronic annotation EVIDENCE CODE ECO:0000203